HPLC System- HSC – HPLC

HSC – HPLC System – Technical Specification

1. System Type:

   • Modular or integrated High-Performance Liquid Chromatography system for qualitative and quantitative analysis of liquid samples.

   • Supports isocratic and gradient operation modes.

2. Pump:

   • High-pressure dual piston reciprocating pump.

   • Flow rate range: 0.001–10.0 mL/min, adjustable in 0.001 mL/min increments.

   • Pressure range: 0–6,000 psi (0–40 MPa) or higher.

   • Flow accuracy: ±1%, flow precision: ±0.2%.

3. Injector System:

   • Manual or auto-injector with variable injection volume (typically 1–100 µL).

   • Optional autosampler for batch sample processing.

4. Column Oven:

   • Temperature range: Ambient +5°C to 80°C, accuracy ±0.1°C.

   • Programmable temperature control for reproducible separation.

5. Detector Options:

   • UV-Visible Detector (190–700 nm)

   • Photodiode Array (PDA) Detector (190–800 nm)

   • Refractive Index (RI) Detector (optional)

   • Fluorescence Detector (FLD) or Conductivity Detector (optional).

6. Degasser:

   • Built-in vacuum degasser with 2–4 channels for solvent degassing.

7. Column Compatibility:

   • Supports standard stainless steel or PEEK columns, 50–300 mm length, 2.1–4.6 mm ID.

   • Quick-connect fittings for easy column change.

8. Solvent System:

   • Up to 4-channel gradient mixing for precise solvent delivery.

   • Compatible with aqueous and organic solvents.

9. Software & Data System:

   • Windows-based chromatography software for data acquisition, integration, and reporting.

   • Features: peak identification, area/height quantification, and calibration curve generation.

   • Real-time monitoring of chromatogram and detector response.

10. Display & Control:

    • Touchscreen or digital LCD interface.

    • Parameters displayed: flow rate, pressure, wavelength, gradient composition, and run time.

11. Power Supply:

    • 220V ±10%, 50/60 Hz, single-phase.

12. Accuracy & Precision:

    • Retention time reproducibility: ±0.1%.

    • Peak area precision: ≤1% RSD.

13. Safety Features:

    • Over-pressure protection, leak sensor, solvent level alarm, and automatic shutdown.

14. Compliance:

    • Conforms to GLP, GMP, and CFR 21 Part 11 data integrity standards.

    • Meets USP, EP, and ISO chromatographic testing requirements.

15. Applications:

    • Ideal for pharmaceutical, food, chemical, environmental, and academic laboratories for compound separation, identification, and quantification.

16. Optional Accessories:

    • Autosampler, column heater/chiller, fraction collector, and online degasser.